Cisd2 agonist 1

CAS No. 2916371-54-3

Cisd2 agonist 1( —— )

Catalog No. M37138 CAS No. 2916371-54-3

Cisd2 agonist 1 is a potent CDGSH iron-sulfur structural domain 2 (CISD2) agonist (EC50: 34 nM) with potential anticancer activity for the study of non-alcoholic fatty liver disease (NAFLD).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 103 Get Quote
5MG 155 Get Quote
10MG 250 Get Quote
25MG 495 Get Quote
50MG 821 Get Quote
100MG 1098 Get Quote
500MG 2205 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Cisd2 agonist 1
  • Note
    Research use only, not for human use.
  • Brief Description
    Cisd2 agonist 1 is a potent CDGSH iron-sulfur structural domain 2 (CISD2) agonist (EC50: 34 nM) with potential anticancer activity for the study of non-alcoholic fatty liver disease (NAFLD).
  • Description
    Cisd2 agonist 1 (Compound 4q) is a Cisd2 agonist (EC50: 34 nM). Cisd2 agonist 1 enhances the Cisd2 expression and improves the pathological changes in the fatty livers. Cisd2 agonist 1 has good metabolic stability. Cisd2 agonist 1 can be used for research of NAFLD.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2916371-54-3
  • Formula Weight
    308.33
  • Molecular Formula
    C14H13FN2O3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (324.33 mM; Ultrasonic )
  • SMILES
    O=C(OC)C1=C(SC(C(=O)NC2=CC=C(F)C=C2)=C1C)N
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Yao CH, et al. Discovery of tetrasubstituted thiophenes as Cisd2 activators: A potential novel therapeutic option in nonalcoholic fatty liver disease. Eur J Med Chem. 2023 Oct 5;258:115583.?
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